I’ve compiled Twig under XNA 3.0 and fix the minor gotchas in the project files and it seems to work.  I’ll put a new cut of the source tree up tomorrow or Wednesday.  In the mean time, I’ve rebuilt the webcomic episodes using ClickOnce deployment, which requires somewhat more than one click for the user, but still prevents you from having to search out and install the various libraries that are needed.  The first time you try a comic episode, you’ll have to wait for it to download the redistributables for .NET 3.5 and XNA 3.0, but after that it will run fairly automatically without your having to manually open zip files, etc.  Let me know if you have any problems.